bremelanotide

A long time ago, in May 2008, I wrote about how PL-6983 is the new version of Bremelanotide after the FDA shot down Palatin Technologies research with Bremelanotide (as a drug for ED and FSD administered with a nasal mist)…

But as it turns out, Palatin Technologies is *still* working on Bremelanotide, except instead of “sniffing” it, a person would inject it into themselves similar to how some Diabetics do injections. Note this does NOT mean injecting Brem into a blood vessel/stream! 

And this week Palatin Technologies published results of the most recent tests with Brem administered in this fashion – and it was GOOD news.   They reported patients reacted similar to those who tried Brem nasally in their old tests but WITHOUT the possible nausea and increased blood pressure that was used by the FDA to stop approval for Bremelanotide when taken the old way.

So now Palatin will go ahead with the next stage of clinical trials (stage 2b) and HOPEFULLY it’ll be available by prescription for people experiencing either erectile disorder or female sexual arousal disorder!

From the press release, here are the offical results of these latest trials:

Key Results

In all subjects, subcutaneous administration of bremelanotide resulted in consistent and predictable plasma concentrations at levels known from previous studies to improve erectile function. Other key results include:

• No statistically significant difference in mean changes in blood pressure was seen in subjects receiving bremelanotide compared to placebo.
• No clinically or statistically significant difference in the range of blood pressure changes was seen in subjects receiving bremelanotide compared to placebo.
• No subject discontinued participation in the study as a result of protocol stopping rules based on blood pressure changes.
• No subject discontinued participation in the study due to nausea.
• No difference in the rate of vomiting observed between subjects receiving bremelanotide compared to placebo (one in each group).

Full press release here.

Stay tuned – I’ll post more when I see it (ie if/when they start those stage 2b trials).

~ Ciao

This entry was posted on Thursday, August 13th, 2009 at 11:06 am and is filed under Uncategorized. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.